Jump to content

Josh

Bunny Guest
  • Posts

    467
  • Joined

  • Last visited

Everything posted by Josh

  1. Probably Andybrann from DI, used to speak to him daily for years and then he dropped off the face of earth
  2. If a 2 week prep then RSD 2011 as most clans didn't have much organisation in 05 compared to later in time, but if it was a spur PK then it would be Corr as RSD wouldn't show. DF because half of DS went there anyway, and Clans got more organised I'd say during the removal of wilderness (ironically) with CWA being the only option. The official Runehq clan vs Zybez Clan chat 2010 Stealing Creations
  3. Should name in Greek to be super edgy
  4. wow vr are very bad from those videos good job df on your victory
  5. The rules were confusing for everyone, constantly changing. Wasn't easy for the public, and certainly not the restaurants. I understand why they did the tiers to try and keep as much of the country moving as possible, and I felt hospitality did it to the best of their ability to keep things safe and maximise their chance of staying open. Just didn't think it was fair to say they didn't care, unless it was just a bad one-off experience which is bound to happen (sadly). I have no idea how the support bubble thing works as it never applied to me (I wasn't a single household, nor did I have any family/relatives to care for/shop for). I mean if I compare the UKs rules to those in Finland (in hospitality venues) then it certainly was safer in the UK, like having a QR code for walk ins. Here there's nothing, or no record of you even being there. Case numbers here are low, sure, but still there's no system
  6. Yes and that person would contact you, or your phone should contact you if you had test & trace app. I can't comment on December, as I left the UK in November, but before then I never had to scan once when I made a reservation, and every single time when I walked in. If the area you were in was Tier 3 area, hospitality was closed to everyone (London moved 16th December). If you were in a tier 2 area you shouldn't have been mixing with different households, so they probably (wrongly) assumed you wouldn't be breaking the law, and that you were the same household. Hospitality was open for same households only. Not a single tier restriction banned walk ins in December 2020, but yeah the whole tier system was confusing, but the point is that walk-ins weren't banned. E: This is all from England, I realise you could be in Scotland/Wales/Northern Ireland who had their own systems to make it even more confusing. E2: Scotland never banned walk ins, https://www.gov.scot/publications/coronavirus-covid-19-protection-levels/pages/protection-level-2/ ; cba to google Wales/Northern Ireland
  7. You had a reservation, they already had your details to contact your party with should there be a positive case. The QR code is for walk-ins which you scan from the track-and-trace app, and only for hospitality (not a food store); Only one person from each group/household needs to scan anyway.
  8. Then either: a) your friend isn't in the medical field, b) you're making it up Unless you have an RNA genome, it is not possible for mRNA to affect your genetic construct. If you had a single stranded genome you'd be dead.
  9. Without being able to comment on the US, the school of thought in Europe is that if vaccines are shown to reduce community transmission (which initial results from Israel indicate, but it'll take time for data to be peer-reviewed) then it is much more likely that there will and can be imposed restrictions based on whether you have been vaccinated or not. Of course this is extremely unlikely to happen in the short term, and wouldn't even be contemplated until everyone has at least had access to the vaccine. The rational is relatively straight forward as viruses constantly mutate, and allowing unvaccinated people to spread the disease increases the risk for a mutation that can possibly negate the effects of a vaccine putting everyone back at square one. Very tangibly, it's like telling someone they can't smoke inside a bar because they're harming everyone around them, people who don't want to be harmed. Again, that's just the school of thought by some senior people in medical ethics. There will almost certainly be court cases at the highest level in each country, but it'll be interesting to follow and likely that there will be a lot of different outcomes in different countries.
  10. No. Trials weren't rushed. There are three trials that are required for the approval of a medicine by all regulatory bodies (FDA, EMA, MHRA etc.) and each trial is designed in partnership with a regulatory body. For Infectious diseases, an MIT study of 406,038 clinical trials between 2000 and 2015 found that there's an attrition rate of 25.2% which is not significantly different to the attrition rate of Covid vaccines that have entered phase 1 through to approval. Phase 1 - Typically looks at toxicology and dosage Phase 2 - Typical looks whether the vaccine can elicit an immune response, as well as side effects Phase 3 - Typically looks at natural infection, as well as any additional side effects in a larger population (more heterogeneous). Clinical trials are often very hard to recruit for, and this is one reason drug discovery takes so long. In the case of Covid-19, this was not the case and clinical trials were over subscribed within days. From the numbers in the MIT paper, you can imagine regulators are typically a bottle neck. There are hundreds of Pharma & Bio-Pharma companies typing to design and coordinate studies with a single regulatory body. As a result, there's often long delays between studies and regulators don't have the capacity to run more trials simultaneously as they're involved with each throughout; You basically have to queue up for each phase. With Covid it was prioritised by the EMA and FDA, meaning you were at the front of the queue for the next trial and didn't have long lag periods between. Additionally, Pharma companies were risking a lot of capital by planning, designing and recruiting for the next phase trial before the results of the first trial were known, and then making any modifications and adjustments to the next study based on the outputs of the previous study when known. Studies are science led and data driven. There is no one-size fits all blueprint in drug development. Finally, Pharma companies were producing large quantities of the vaccine whilst the studies were ongoing so in the event of approval there is stock to immediately distribute. Capital was being risked because all of that would be thrown away should a drug fail as seen with Merck. By everyone (Regulators, Pharmaceutical Companies, General Public, Governments) having the same prioritised goal and doing steps simultaneously rather than sequentially it's possible to shave a huge amount of time off the clinical process without risking safety. If you want to have an educated data-driven conversation then I'm happy to entertain you, but so far you've produced nothing of substance. No matter how often you repeat what you read on qanon's website doesn't make it become true. I've worked as a CRA in clinical studies and hold a postgraduate with a focus on Immunology. I'm all for trolling runescape battles, but there's a line when baseless trolling has dangerous implications on peoples health.
  11. Produced? No. Most vaccines built upon a similar underlying technology (e.g mRNA, viral vector) will have a similar production time. It isn't possible to speed up production beyond increasing infrastructure.
  12. Ok this might be really shocking, but not everything you read on the internet is true... You're better off to find peer-reviewed papers, or statistics/figures that are validated by an independent body (e.g those published by THL)
  13. What was rushed? How is saving someone's life not necessary?
  14. There isn't really an ideal way, I remember these things popped up often over the years. Skilling just has people in such basic gear it's not worth pking them. When hunter came out you could go kill someone hunting lizards and you'd get a net and a rope as a drop. They would need a system like BH where you can only access the best skill areas if you are risking X amount of value and have a red skull over your head (e.g 75k or 100k). Even then xp rates would need to be so substantially higher to incentivise people, Jagex probably wouldn't add them (e.g if the fastest WC xp in the game is 100k per hour, you'd need to have 150k or 200k per hour). As for bosses, people would probably find a way to rag them, otherwise they'd just not bother and it'd be dead content. Skilling is probably the best chance... It's too hard to change the mentality which used to be so xp/hour focused (at least in 2012)
×
  • Create New...